{"id":106270,"date":"2024-04-04T13:54:13","date_gmt":"2024-04-04T11:54:13","guid":{"rendered":"https:\/\/efecomunica.efe.com\/?p=106270"},"modified":"2024-04-04T13:54:13","modified_gmt":"2024-04-04T11:54:13","slug":"the-lancet-publishes-results-of-the-phergain-clinical-trial-on-breast-cancer","status":"publish","type":"post","link":"https:\/\/efecomunica.efe.com\/en\/the-lancet-publishes-results-of-the-phergain-clinical-trial-on-breast-cancer\/","title":{"rendered":"The Lancet publishes results of the PHERGain clinical trial on breast cancer"},"content":{"rendered":"<p>Barcelona, April 4 (EFE) &#8211; The medical specialty journal <strong>The Lancet<\/strong> has published the results of the <strong>PHERGain clinical trial<\/strong>, conducted by <strong>MEDSIR<\/strong>, showing that one-third of patients with localized HER2-positive breast cancer could be cured without the need for chemotherapy.<\/p>\n<p>The study highlighted that the early assessment of the response to exclusive preoperative treatment without chemotherapy, using trastuzumab and pertuzumab and employing PET-CT scans, was able to identify <strong>around 40%<\/strong> of such patients who achieved a complete pathological response.<\/p>\n<p>MEDSIR&#8217;s co-founder and senior scientific leader, <strong>Dr. Javier Cort\u00e9s,<\/strong> stressed the significance of the publication in The Lancet, noting its practical implications for patient well-being.<\/p>\n<p><span class=\"embed-youtube\" style=\"text-align:center; display: block;\"><iframe class=\"youtube-player\" width=\"800\" height=\"450\" src=\"https:\/\/www.youtube.com\/embed\/NObVvl8SvQ4?version=3&#038;rel=1&#038;showsearch=0&#038;showinfo=1&#038;iv_load_policy=1&#038;fs=1&#038;hl=en-US&#038;autohide=2&#038;wmode=transparent\" allowfullscreen=\"true\" style=\"border:0;\" sandbox=\"allow-scripts allow-same-origin allow-popups allow-presentation allow-popups-to-escape-sandbox\"><\/iframe><\/span><\/p>\n<h2>Results from 45 centres in seven European countries<\/h2>\n<p>The research, led by Dr. Cort\u00e9s along with Drs. <strong>Antonio Llombart-Cussac<\/strong> and <strong>Jos\u00e9 P\u00e9rez<\/strong>, involved researchers from 45 centers across seven European countries and included a total of 356 patients with localized HER2-positive breast cancer.<\/p>\n<p>Of these, 94.8% of the patients who followed the adaptive therapeutic strategy, whether they received chemotherapy or not, remained c<strong>ancer-free three years after undergoing surgery following treatment<\/strong>. This percentage is even higher (96.4%) among patients who did not require chemotherapy, as only one experienced a local relapse.<\/p>\n<blockquote><p>&#8220;We have seen that we can offer less treatment to a group of patients who have always required <strong>chemotherapy<\/strong>, which optimizes the patients&#8217; <strong>quality of life<\/strong>,&#8221; Cort\u00e9s told EFE in an interview, adding that this strategy does not compromise cure rates.<\/p><\/blockquote>\n<p><span style=\"font-size: 16px;\">Dr. Cort\u00e9s highlighted the benefits of precision medicine and adaptive clinical trials, which focus on the individual patient, noting, <\/span><strong style=\"font-size: 16px;\">&#8220;each patient and each disease is unique.&#8221;<\/strong><\/p>\n<div class=\"tiled-gallery type-rectangular tiled-gallery-unresized\" data-original-width=\"800\" data-carousel-extra='{&quot;blog_id&quot;:1,&quot;permalink&quot;:&quot;https:\\\/\\\/efecomunica.efe.com\\\/en\\\/the-lancet-publishes-results-of-the-phergain-clinical-trial-on-breast-cancer\\\/&quot;,&quot;likes_blog_id&quot;:186910745}' itemscope itemtype=\"http:\/\/schema.org\/ImageGallery\" > <div class=\"gallery-row\" style=\"width: 800px; height: 227px;\" data-original-width=\"800\" data-original-height=\"227\" > <div class=\"gallery-group images-1\" style=\"width: 400px; height: 227px;\" data-original-width=\"400\" data-original-height=\"227\" > <div class=\"tiled-gallery-item tiled-gallery-item-large\" itemprop=\"associatedMedia\" itemscope itemtype=\"http:\/\/schema.org\/ImageObject\"> <a href=\"https:\/\/efecomunica.efe.com\/en\/the-lancet-publishes-results-of-the-phergain-clinical-trial-on-breast-cancer\/medsir-the-lancet-cancer-her2-5\/\" border=\"0\" itemprop=\"url\"> <meta itemprop=\"width\" content=\"396\"> <meta itemprop=\"height\" content=\"223\"> <img loading=\"lazy\" decoding=\"async\" class=\"\" data-attachment-id=\"106277\" data-orig-file=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-5.jpg\" data-orig-size=\"1920,1080\" data-comments-opened=\"\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"MEDSIR &amp;#8211; The Lancet Cancer HER2 (5)\" data-image-description=\"&lt;p&gt;MEDSIR co-founder and senior scientific leader Dr. Javier Cort\u00e9s during an interview with Agencia EFE. EFE.&lt;\/p&gt; \" data-medium-file=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-5-300x169.jpg\" data-large-file=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-5-1024x576.jpg\" src=\"https:\/\/i0.wp.com\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-5.jpg?w=396&#038;h=223&#038;ssl=1\" srcset=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-5.jpg 1920w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-5-300x169.jpg 300w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-5-1024x576.jpg 1024w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-5-768x432.jpg 768w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-5-1120x630.jpg 1120w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-5-1536x864.jpg 1536w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-5-430x242.jpg 430w\" width=\"396\" height=\"223\" loading=\"lazy\" data-original-width=\"396\" data-original-height=\"223\" itemprop=\"http:\/\/schema.org\/image\" title=\"MEDSIR - The Lancet Cancer HER2 (5)\" alt=\"MEDSIR co-founder and senior scientific leader Dr. Javier Cort\u00e9s during an interview with Agencia EFE. EFE.\" style=\"width: 396px; height: 223px;\" \/> <\/a> <div class=\"tiled-gallery-caption\" itemprop=\"caption description\"> MEDSIR co-founder and senior scientific leader Dr. Javier Cort\u00e9s during an interview with Agencia EFE. EFE. <\/div> <\/div> <\/div> <!-- close group --> <div class=\"gallery-group images-1\" style=\"width: 400px; height: 227px;\" data-original-width=\"400\" data-original-height=\"227\" > <div class=\"tiled-gallery-item tiled-gallery-item-large\" itemprop=\"associatedMedia\" itemscope itemtype=\"http:\/\/schema.org\/ImageObject\"> <a href=\"https:\/\/efecomunica.efe.com\/en\/the-lancet-publishes-results-of-the-phergain-clinical-trial-on-breast-cancer\/medsir-the-lancet-cancer-her2-1\/\" border=\"0\" itemprop=\"url\"> <meta itemprop=\"width\" content=\"396\"> <meta itemprop=\"height\" content=\"223\"> <img loading=\"lazy\" decoding=\"async\" class=\"\" data-attachment-id=\"106278\" data-orig-file=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-1.jpg\" data-orig-size=\"1920,1080\" data-comments-opened=\"\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"MEDSIR &amp;#8211; The Lancet Cancer HER2 (1)\" data-image-description=\"&lt;p&gt;MEDSIR workers at the company headquarters in Barcelona. EFE&lt;\/p&gt; \" data-medium-file=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-1-300x169.jpg\" data-large-file=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-1-1024x576.jpg\" src=\"https:\/\/i0.wp.com\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-1.jpg?w=396&#038;h=223&#038;ssl=1\" srcset=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-1.jpg 1920w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-1-300x169.jpg 300w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-1-1024x576.jpg 1024w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-1-768x432.jpg 768w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-1-1120x630.jpg 1120w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-1-1536x864.jpg 1536w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-1-430x242.jpg 430w\" width=\"396\" height=\"223\" loading=\"lazy\" data-original-width=\"396\" data-original-height=\"223\" itemprop=\"http:\/\/schema.org\/image\" title=\"MEDSIR - The Lancet Cancer HER2 (1)\" alt=\"MEDSIR workers at the company headquarters in Barcelona. EFE\" style=\"width: 396px; height: 223px;\" \/> <\/a> <div class=\"tiled-gallery-caption\" itemprop=\"caption description\"> MEDSIR workers at the company headquarters in Barcelona. EFE <\/div> <\/div> <\/div> <!-- close group --> <\/div> <!-- close row --> <div class=\"gallery-row\" style=\"width: 800px; height: 452px;\" data-original-width=\"800\" data-original-height=\"452\" > <div class=\"gallery-group images-1\" style=\"width: 800px; height: 452px;\" data-original-width=\"800\" data-original-height=\"452\" > <div class=\"tiled-gallery-item tiled-gallery-item-large\" itemprop=\"associatedMedia\" itemscope itemtype=\"http:\/\/schema.org\/ImageObject\"> <a href=\"https:\/\/efecomunica.efe.com\/en\/the-lancet-publishes-results-of-the-phergain-clinical-trial-on-breast-cancer\/medsir-the-lancet-cancer-her2-4\/\" border=\"0\" itemprop=\"url\"> <meta itemprop=\"width\" content=\"796\"> <meta itemprop=\"height\" content=\"448\"> <img loading=\"lazy\" decoding=\"async\" class=\"\" data-attachment-id=\"106279\" data-orig-file=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-4.jpg\" data-orig-size=\"1920,1080\" data-comments-opened=\"\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;0&quot;}\" data-image-title=\"MEDSIR &amp;#8211; The Lancet Cancer HER2 (4)\" data-image-description=\"\" data-medium-file=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-4-300x169.jpg\" data-large-file=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-4-1024x576.jpg\" src=\"https:\/\/i0.wp.com\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-4.jpg?w=796&#038;h=448&#038;ssl=1\" srcset=\"https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-4.jpg 1920w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-4-300x169.jpg 300w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-4-1024x576.jpg 1024w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-4-768x432.jpg 768w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-4-1120x630.jpg 1120w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-4-1536x864.jpg 1536w, https:\/\/efecomunica.efe.com\/wp-content\/uploads\/2024\/04\/MEDSIR-The-Lancet-Cancer-HER2-4-430x242.jpg 430w\" width=\"796\" height=\"448\" loading=\"lazy\" data-original-width=\"796\" data-original-height=\"448\" itemprop=\"http:\/\/schema.org\/image\" title=\"MEDSIR - The Lancet Cancer HER2 (4)\" alt=\"MEDSIR co-founder and senior scientific leader Dr Javier Cort\u00e9s (left) talks to one of his colleagues after an interview with Agencia EFE. EFE\" style=\"width: 796px; height: 448px;\" \/> <\/a> <div class=\"tiled-gallery-caption\" itemprop=\"caption description\"> MEDSIR co-founder and senior scientific leader Dr Javier Cort\u00e9s (left) talks to one of his colleagues after an interview with Agencia EFE. EFE <\/div> <\/div> <\/div> <!-- close group --> <\/div> <!-- close row --> <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Barcelona, April 4 (EFE) &#8211; The medical specialty journal The Lancet has published the results of the PHERGain clinical trial, conducted by MEDSIR, showing that one-third of patients with localized [&hellip;]<\/p>\n","protected":false},"author":198164088,"featured_media":106276,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[123780],"tags":[],"class_list":["post-106270","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - 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